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We conducted a phase 3 trial to confirm the efficacy and safety of terlipressin plus albumin in adults with HRS1 - Information from www.nejm.org

Background Metformin is a logical treatment for women with gestational diabetes mellitus but randomized trials to assess the efficacy and  - Information from www.nejm.org

Esophagitis occurs when excessive reflux of acid and pepsin results in necrosis of surface layers of esophageal mucosa causing erosions and  - Information from www.nejm.org

Review ArticleGlobal Health food yields and nutritional health will be impaired Effects of Globalization on Population Health - Information from www.nejm.org

The New England Journal of Medicine (NEJM) is a weekly general medical journal that publishes new medical research and review articles and editorial  - Information from www.nejm.org

Continue wine and milk milk 1 AM Dec 23d—Pulse 170 and up wards and difficult to count resp ment for the radical cure of " fistula in - Information from www.nejm.org

Abstract Although prostaglandin D2 is the most abundant prostanoid generated by human lung mast cells and causes bronchoconstriction in  - Information from www.nejm.org

No treatment is necessary unless there is associated pinpoint bleeding in which case simple electrofulguration of the symptomatic lesions is  - Information from www.nejm.org

Background Adjuvant chemotherapy is standard treatment for patients with resected colon cancer who are at high risk for recurrence  - Information from www.nejm.org

reportedly revealed mildly distended fluidfilled loops of small bowel in the suprapubic region without guarding rigidity distention or masses - Information from www.nejm.org

51 References 339 Citing Articles Letters Related Articles Abstract Background A decade ago the administrative costs of health care  - Information from www.nejm.org

Alternative Science and Human Reproduction List of authors R Alta Charo JD July 27 2017 N Engl J Med 2017 377:309311 DOI: 101056/NEJMp1707107  - Information from www.nejm.org

Bismarck Pirogoff and the German Empire or How the Map of Europe Might Have Been Changed through the Application of a Spanish Fly Blister - Information from www.nejm.org

C perfringens produces a phospholipase that causes intravascular hemolysis Clostridial sepsis would explain the intravascular hemolysis  - Information from www.nejm.org

Telltale signs of chronic alcohol ingestion are precipitous decreases in plasma concentrations of phosphate magnesium potassium and calcium  - Information from www.nejm.org

Endometritis and toxic shock syndrome associated with Clostridium sordellii have previously been reported after childbirth and in one case after medical  - Information from www.nejm.org

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Abstract Background The effects of spinal anesthesia as compared with general anesthesia on the ability to walk in older adults undergoing  - Information from www.nejm.org

that promote grand mal myoclonic–tonic–clonic convulsions3 diffuse highamplitude polyspikes awakening myoclonic seizures and polyspike - Information from www.nejm.org

Background Chemotherapy for metastatic lung or colorectal cancer can Educational level functional status and the patients role in  - Information from www.nejm.org

CVT Yes No Yes Yes Yes Yes Yes Yes Yes Yes Pending† Splanchnicvein thrombosis‡ Yes No No No Yes No No No No Yes No - Information from www.nejm.org

Abstract Background Until very recently vaccines against severe acute respiratory syndrome coronavirus 2 (SARSCoV2) had not been  - Information from www.nejm.org

How Structural Racism Works As a legacy of African enslavement the policies and institutions that undergird the US racial hierarchy - Information from www.nejm.org

Abstract Background Heavychargedparticle radiation has several advantages over protons and photons for the treatment of intracranial  - Information from www.nejm.org

Exercise capacity was measured in metabolic equivalents (MET) could be incorporated into the interpretation of exercise stress tests  - Information from www.nejm.org

Logisticregression analysis was used to evaluate the ability of PET and CT to identify malignant mediastinal lymph nodes - Information from www.nejm.org

regarding whether volumebased lowdose computed tomographic (CT) screening can reduce lungcancer mortality among male former and - Information from www.nejm.org

The New England Journal of Medicine (NEJM) is a weekly general medical journal that publishes new medical research and review articles and editorial  - Information from www.nejm.org

Abstract Background Thrombotic thrombocytopenic purpura is an uncommon disease with a high mortality rate even with current treatment - Information from www.nejm.org

The primary end point was the late asthmatic response responses and persistent airway inflammation in patients with allergic asthma - Information from www.nejm.org

Necrotizing fasciitis type II is a monomicrobial infection (Table 1) · Two distinct clinical presentations have been described: infection with a  - Information from www.nejm.org

There were no significant differences between the groups with respect to any of the five items on our sleep questionnaire There was no  - Information from www.nejm.org

Baden MD Brian T Chan MD MPH Brigham and Womens Hospital Boston MA Bruce D Walker MD Ragon Institute of MGH  - Information from www.nejm.org

Whereas erythrocytes in irondeficiency anemia are often small (low mean corpuscular volume) and hemoglobindeficient (low mean corpuscular  - Information from www.nejm.org

Health — Combating the US Opioid Crisis CL Barry et al similar to that recommended by Gyawali and Fass for managing the care  - Information from www.nejm.org

Peripancreatic lymph node enlargement is common as are sclerosing cholangitislike changes in the bile duct The levels of pancreatic enzymes are usually  - Information from www.nejm.org

their practice and prepare for board exams opens in new tab Pharmaceuticals for Human Use Good Clinical Practice guidelines  - Information from www.nejm.org

Pathologic Antibodies to Platelet Factor 4 after ChAdOx1 nCoV19 Vaccination List of authors Marie Scully MD Deepak Singh BSc Robert  - Information from www.nejm.org

and among those who received a diagnosis of antibioticassociated hemorrhagic colitis stool samples were cultured for K oxytoca - Information from www.nejm.org

THE secretion of melatonin from the pineal gland is linked to the development have plasma melatonin concentrations lower than those of  - Information from www.nejm.org

Alice T Shaw MD PhD SaiHong I Ou MD PhD YungJue Bang MD PhD N Engl J Med 2014 371:19631971 - Information from www.nejm.org

No information is available for this page - Information from www.nejm.org

Background Vitamin D supplementation for the prevention of rickets is one of the oldest and most effective prophylactic measures in medicine  - Information from www.nejm.org

Panels A through D are radiographs included with the publication of the Berlin definition that meet the diagnostic criteria for ARDS The  - Information from www.nejm.org

IN the late afternoon of June 9 1953 a tornado unexpectedly struck a section of Worcester County Massachusetts and in about twenty minutes created a  - Information from www.nejm.org

Abstract Background Sodium–glucose cotransporter 2 (SGLT2) inhibitors reduce the risk of hospitalization for heart failure or death from  - Information from www.nejm.org

Increased deadspace fraction is a feature of the early phase of the acute respiratory distress syndrome Elevated values are associated with an  - Information from www.nejm.org

Background The metabolic effects and mechanism of action of metformin are still poorly understood despite the fact that it has been used to  - Information from www.nejm.org

The New England Journal of Medicine (NEJM) is a weekly general medical journal that publishes new medical research and review articles and editorial  - Information from www.nejm.org

Antibodybased therapies include convalescent plasma hyperimmune globulin and monoclonal antibodies For many infectious diseases treatment  - Information from www.nejm.org

The GBD 2015 Obesity Collaborators bodymass index (BMI) according to age sex cause and BMI in 195 countries between 1990 and 2015 - Information from www.nejm.org

Amaurosis fugax a brief loss of vision in one eye is caused by hypoperfusion of the retinal circulation If an attack of amaurosis is  - Information from www.nejm.org

When the Journal took up the topic in 2003 with a debate about the role of race in medicine one side argued that racial and ethnic categories  - Information from www.nejm.org

The New England Journal of Medicine (NEJM) is a weekly general medical journal that publishes new medical research and review articles and editorial  - Information from www.nejm.org

Radial arterial lines are important tools in the treatment of After the risks of the procedure have been appropriately assessed and  - Information from www.nejm.org

Hepatic encephalopathy is a chronically debilitating complication of hepatic cirrhosis The efficacy of rifaximin a minimally absorbed  - Information from www.nejm.org

N Engl J Med 2013 368:13351343 DOI: 101056/NEJMra1109341 Article Figures/Media Metrics 50 References 278 Citing Articles Letters  - Information from www.nejm.org

contusions diffuse brain swelling or hydrocephalus consulting fees from PresSura Calico Glide Pharma Pfizer Medicxi Ventures  - Information from www.nejm.org

Papers and Discussions from The New England Journal of Medicine — Chemical Evidences of Alcoholic Intoxication and Their MedicoLegal Significance - Information from www.nejm.org

He was a smoker with a 30packyear history and he drank alcohol socially there was no injectiondrug use His family history included  - Information from www.nejm.org

In summary singledose cefixime may now be the preferred choice for initial treatment of uncomplicated gonorrhea unless the lower cost of the  - Information from www.nejm.org

The pleural space is defined by the visceral pleura which covers the lung and the parietal pleura which covers the chest wall diaphragm  - Information from www.nejm.org

Ultrasonography helps to ensure safe and successful insertion of an arterial catheter This video demonstrates the use of ultrasound  - Information from www.nejm.org

Abstract Background Mortality is very high in lactic acidosis and there is no satisfactory treatment other than treatment of the  - Information from www.nejm.org

CARDIOPULMONARY arrest can be defined as the abrupt cessation of spontaneous and effective ventilation and systemic perfusion (circulation) - Information from www.nejm.org

Abstract Background Chronic edema of the leg is a risk factor for cellulitis Daily use of compression garments on the leg has been  - Information from www.nejm.org

A patient with preexisting cardiac disease died the day after discharge from an unspecified cause One patient who had a history of pericarditis  - Information from www.nejm.org

Background Although much is known about the natural history of systemic lupus erythematosus (SLE) the development of SLE autoantibodies  - Information from www.nejm.org

patients discharged with congestive heart failure or pneumonia variation in readmission rates for congestive heart failure (28%  - Information from www.nejm.org

Ultrasonography demonstrated a contracted gallbladder containing a stone Endoscopic retrograde cholangiography showed no stones in the  - Information from www.nejm.org

The New England Journal of Medicine (NEJM) is a weekly general medical journal that publishes new medical research and review articles and editorial - Information from www.nejm.org

Available in both paper and digital formats NEJM reprints can be ready to distribute within two weeks of article publication and — in some cases — on the  - Information from www.nejm.org

Eric Song MS Takehiro Takahashi MD PhD Manabu Taura PhD OrrEl Weizman BA Patrick Wong MS Yexin Yang BS - Information from www.nejm.org

Electrocardiographic artifact can simulate ventricular tachycardia to case reports1–7 proposed classifications89 and diagnostic - Information from www.nejm.org

The focus of genomics research has recently moved beyond analyzing DNA variation to studying patterns of gene expression in individual cells a  - Information from www.nejm.org

identifies this doctor afield on its title page with the following legend: "Peter Mark Roget MD Secretary to the Royal Society Fullerian Professor  - Information from www.nejm.org

Selected Papers from The New England Journal of Medicine — Radium Therapy in Hyperthyroidism with Observations on the Endocrinous System - Information from www.nejm.org

It seems that the rare cutaneous hypersensitivity reactions among recipients of mRNA vaccines are responses to the translated spike protein  - Information from www.nejm.org

Abstract Background Psilocybin may have antidepressant properties but direct comparisons between psilocybin and established treatments for  - Information from www.nejm.org

Acute kidney injury is a potential complication of severe rhabdomyolysis regardless of whether the rhabdomyolysis is the result of trauma or  - Information from www.nejm.org

Acute kidney injury is a potential complication of severe rhabdomyolysis regardless of whether the rhabdomyolysis is the result of trauma  - Information from www.nejm.org

Rhabdomyolysis and Acute Kidney Injury Review Article N Engl J Med 2009361:6272 In the title of Table 2 (page 67) “Microscopic” should  - Information from www.nejm.org

In two patients with rhabdomyolysis and acute kidney injury the mean serum myoglobin clearance with a single dialysis treatment was 59% A 4  - Information from www.nejm.org

BackgroundStudies have suggested that sickle cell trait elevates the risks of exertional rhabdomyolysis and death We conducted a study of  - Information from www.nejm.org

Abstract Rhabdomyolysis with myoglobinuria from nontraumatic causes was the sole identifiable explanation for acute renal failure in 15  - Information from www.nejm.org

Abstract Because an increasing number of patients were arriving at our emergency room with cocaine intoxication and rhabdomyolysis  - Information from www.nejm.org

The action of the extensor and flexor muscles is simultaneous and equally balanced presenting the appearance when walking of almost complete anchylosis  - Information from www.nejm.org

The discovery of phosphatidylinositol 3kinase (PI3K) changed the way we view and understand growthfactor signaling - Information from www.nejm.org

Nicole Marten RN Ryan Zarychanski MD Lauren E Kelly Plan Spending after State SpecialtyDrug OutofPocket Spending Caps - Information from www.nejm.org

Clinical Lecture from The New England Journal of Medicine — Acute Parenchymatous Nephritis — Lecture Delivered at the Philadelphia Hospital - Information from www.nejm.org

COMMITTEE ON MATERNAL WELFARE* Cesarean Section Followed by Generalized of an unengaged presenting part with contractions that remained irregular - Information from www.nejm.org

Beyond medications that control glycemia and blood pressure filtration pressure which in a patient with intraglomerular hypertension  - Information from www.nejm.org

ing to registration of the drug under the name Aspirin by Friedrich Bayer and the paradoxical effect of SA on kidney urate excretion: - Information from www.nejm.org

Abstract Background Bleeding in early pregnancy is strongly associated with pregnancy loss Progesterone is essential for the maintenance of  - Information from www.nejm.org

of the large numbers of tourists and students who arrive in the country each summer predominantly from Europe and mainland China - Information from www.nejm.org

But its important to recognize that racial/ethnic disparities are defined in terms of social not biologic classifications and therefore such  - Information from www.nejm.org

Editorial from The New England Journal of Medicine — The Leucocytes of Human Blood — Annual Report of the Massachusetts General Hospital — Medical Notes - Information from www.nejm.org

THIS SITE USES COOKIES to personalize content to measure website and advertising performance and to present relevant advertising By  - Information from www.nejm.org

The current clinical strategy for diagnosing genital herpes simplex virus indicative of urogenital or anal infection with HSV type 1 - Information from www.nejm.org

superficial excoriation of a large proportion of superficial cancers (rodent Should any excoriations be thus produced they may be protected by a - Information from www.nejm.org

Woltmans Sign of Hypothyroidism A 53yearold man presented to the endocrinology clinic with fatigue and sensitivity to cold A physical  - Information from www.nejm.org

Endoscopic ultrasonography showed an unchanged mass in the porta hepatis a decrease in Multiple lymph nodes were seen in the porta hepatis and in the  - Information from www.nejm.org

Clinical Practice and Review · publication image Clinical Practice Latent Tuberculosis Infection M Shah and SE Dorman · Perspective Inequitable Access to  - Information from www.nejm.org

Abstract Stiffman syndrome is a rare disorder of the central nervous system of unknown pathogenesis We have previously reported the  - Information from www.nejm.org

The New England Journal of Medicine (NEJM) is a weekly general medical journal that publishes new medical research and review articles and editorial  - Information from www.nejm.org

Background Postoperative chemoradiotherapy is the recommended standard therapy for patients with locally advanced rectal cancer - Information from www.nejm.org

as measured by the Psoriasis Area Severity Index (PASI) and by subjective evaluation as assessed with patientreported outcome sca - Information from www.nejm.org

After the procedure 25 patients had hepatic encephalopathy as compared with 20 patients before the procedure although encephalopathy improved  - Information from www.nejm.org

To the Editor: Postpolycythemic myeloid metaplasia is characterized by increasing splenomegaly dacryocytes anemia extensive bone marrow  - Information from www.nejm.org

Total mucin concentrations in sputum were measured with the use of sizeexclusion chromatography and refractometry In 148 of these participants  - Information from www.nejm.org

The FDA has issued a warning regarding use of general anesthetic and sedation drugs in children under 3 years of age and in pregnant women  - Information from www.nejm.org

Previous studies have suggested a benefit to intervention with ablation before drug failure because a shorter “diagnosistoablation” time is  - Information from www.nejm.org

The mean (±SD) volume of total blood transfused per child was 475±385 ml and 353±348 ml respectively 197 children (123%) and 300 children  - Information from www.nejm.org

each of the NCC MERP Index categories are pro vided in the Supplementary Appendix available with the full text of this article at NEJMorg  - Information from www.nejm.org

Neeltje van Doremalen PhD Trenton Bushmaker BSc National Institute of Allergy and Infectious Diseases Hamilton MT Dylan H Morris M - Information from www.nejm.org

The theory of spontaneous generation was long since proposed to account for the origin of beings whose germs were too minute - Information from www.nejm.org

The remainder of the neurologic examination was normal contrast material revealed a left adrenal nodule measuring 12 cm in diameter - Information from www.nejm.org

A Cox proportionalhazards regression model with timedependent covariates was used to estimate the association of booster status with death due  - Information from www.nejm.org

The most recent assessment of the global burden of disease is the 2010 study (GBD 2010) which provides results for 1990 2005 and 2010 - Information from www.nejm.org

These properties make PDL1 a potentially promising target for cancer immunotherapy BMS936559 is a highaffinity fully human PDL1–specific  - Information from www.nejm.org

His symptoms did not respond to treatment with oral cephalexin Physical examination showed a temperature of 389°C a small pustule on the left  - Information from www.nejm.org

telehealth evidence base and to assist physicians opment of the Telehealth Usability Questionnaire (TUQ) Int J - Information from www.nejm.org

Dr Mubeen A Shakir (Medicine): A 50yearold woman was admitted to this hospital because of pain in the left upper quadrant and hypoxemia - Information from www.nejm.org

The New England Journal of Medicine (NEJM) is a weekly general medical journal that publishes new medical research and review articles and editorial  - Information from www.nejm.org

The new public charge rule which went into effect on February 24 2020 states that “aliens are inadmissible to the United States if they  - Information from www.nejm.org

Of 14 patients who had left ventricular dysfunction on echocardiography during admission 10 still had such dysfunction at the time of hospital - Information from www.nejm.org

Abstract Background Previous studies showed a higher incidence of lung cancer among young women than among young men in the United States - Information from www.nejm.org

The mortality ratio (the rate of mortality from cancer in these patients as compared with that in the general population) was 090 (95 percent  - Information from www.nejm.org

Helga Wanglie an 86yearold Minneapolis woman died of sepsis on July 4 after being in a persistent vegetative state for over a year - Information from www.nejm.org

BCL11A is a transcription factor that represses γglobin expression and fetal hemoglobin in erythroid cells We performed electroporation of  - Information from www.nejm.org

Lifetime Risk of Stroke in the Global Burden of Disease Study April 4 2019 N Engl J Med 2019 380:13771378 DOI: 101056/NEJMc1900607 Related Articles - Information from www.nejm.org

these babies were similar to the postmature infants discussed by Clifford tion to Cliffords "postmaturity syndrome" and the - Information from www.nejm.org

The World Health Organization recommends transfusion of 20 ml of wholeblood equivalent per kilogram of body weight for anemia regardless of  - Information from www.nejm.org

Archive September 11 1958 · Original Articles · Special Article · Medical Progress · Medical Intelligence · Case Records of the Massachusetts General Hospital - Information from www.nejm.org

The corresponding decrease in the percentage of male enrollees most notably White The percentages of enrollees from Black Hispanic  - Information from www.nejm.org

A video shows Quinckes sign in an area of exuberant dermatitis due to insect bites to the knee Jeffrey D Lazar MD MPH Lucy K Willis  - Information from www.nejm.org

An Association between Air Pollution and Mortality in Six US Cities List of authors Douglas W Dockery C Arden Pope Xiping Xu John D - Information from www.nejm.org

Mucosal biopsies from the terminal ileum of one brother were normal on light and electron microscopy Intrinsic factor markedly stimulated  - Information from www.nejm.org

PURPURA is a heterogeneous group of diseases with a single common denominator of spontaneous extravasation of blood Classically the purpuras are divided  - Information from www.nejm.org

A NEURYSMS of the superior pancreaticoduodenal artery are extremely rare surgical lesions In 1952 Sampsel et al1 reported a case of aneurysm involving an  - Information from www.nejm.org

reversetranscriptase polymerase chain reaction (RTqPCR) to detect SARSCoV2 to Dr Vogel) from the Dutch Research Council (NWO) - Information from www.nejm.org

We estimated risks using the Kaplan–Meier estimator The excess number of events per 1000 persons for BNT162b2 as compared with  - Information from www.nejm.org

curacy of gradedcompression ultrasonography and its effect on the care of patients thought to have ap pendicitis - Information from www.nejm.org

Pignets Standard and Chinese Students List of authors March 2 1916 Boston Med Surg J 1916 174:329330 DOI: 101056/NEJM191603021740914 - Information from www.nejm.org

AIP Mutation in Pituitary Adenomas in the 18th Century and Today List of authors Harvinder S Chahal MB BS References (34) - Information from www.nejm.org

A mobility assessment is an important component of the overall assessment of wellbeing in an older person A change in mobility or walking  - Information from www.nejm.org

Background Sustained cardiac adrenergic stimulation has been Synergistic Polymorphisms of β1 and α2CAdrenergic Receptors and the Risk  - Information from www.nejm.org

The New England Journal of Medicine (NEJM) is a weekly general medical journal that publishes new medical research and review articles and editorial  - Information from www.nejm.org

Hematopoietic Stem and ProgenitorCell Gene Therapy for Hurler Syndrome Medicine and Society Hidden in Plain Sight — Reconsidering the  - Information from www.nejm.org

Abstract We studied the relation of plasma renin activity to serum levels of ionized calcium and magnesium in 102 normotensive patients and  - Information from www.nejm.org

The New England Journal of Medicine (NEJM) is a weekly general medical journal that publishes new medical research and review articles and editorial  - Information from www.nejm.org

The differential diagnosis of sudden painless vision loss includes vitreous hemorrhage retinal artery or vein occlusion retinal detachment  - Information from www.nejm.org

Chess and Thomas report findings from their New York Longitudinal Study which followed 133 subjects from early infancy to young adulthood - Information from www.nejm.org

To the Editor: The images of massive obesity simulating clearly shows the condition of lipomatosis of the legs also known as lipedema - Information from www.nejm.org

ent gynecomastia due to puberty (25 percent) drugs Danazol has also been studied in several uncontrolled - Information from www.nejm.org

From the global public health perspective the initial primary two studies evaluated the effect of the booster by comparing the risk  - Information from www.nejm.org

Alzheimers Therapeutic Research Institute San Diego CA Gary Romano MD PhD Janssen Research and Development Titusville NJ  - Information from www.nejm.org

For the Sake of Inquiry and Knowledge — The Inevitability of Open Access Many stakeholders in the scholarly communication system have cause to  - Information from www.nejm.org

Joyce OShaughnessy MD Cynthia Osborne MD John E Pippen MD Mark Yoffe MD Debra Patt MD Christine Rocha MSc  - Information from www.nejm.org

Background Infliximab a monoclonal antibody against tumor necrosis factor is an effective maintenance therapy for patients with Crohns disease without  - Information from www.nejm.org

90 of 317 patients [284%] P0007) On endoscopy fewer patients in the omeprazole group had actively bleeding ulcers (12 of 187 vs - Information from www.nejm.org

These observations indicate a potential risk of illness after successful vaccination and subsequent infection with variant virus  - Information from www.nejm.org

View Current Issue December 9 2021 Vol 385 No 24 · Browse Full Issue Index » xml · Gingival Melanoma EM Varoni and S Decani - Information from www.nejm.org

Background Participation of women in the medical profession has increased during the past four decades but issues of concern persist  - Information from www.nejm.org

Abstract Background Populationbased data from the United States on the effectiveness of the three coronavirus disease 2019 (Covid19)  - Information from www.nejm.org

Baroreceptors in each carotid sinus send information about distention of the vessel wall by the glossopharyngeal nerves to the brain stem - Information from www.nejm.org

Genetic variation in the region upstream from the transcription initiation site of the gene encoding B lymphoid tyrosine kinase (BLK) and  - Information from www.nejm.org

Papers and Discussions from The New England Journal of Medicine — Certain Diagnostic Aspects of MedicoSurgical Diseases of the Gastrointestinal Tract - Information from www.nejm.org

As many as half of US patients dont take medications as prescribed and the rates are similar after myocardial infarction - Information from www.nejm.org

Regulating Academic–Industrial Research Relationships — Solving Problems or Stifling Progress? Dr Thomas Stossel argues for increasing  - Information from www.nejm.org

A Possible Role for Antiidiotype Antibodies in SARSCoV2 Infection and Vaccination WJ Murphy et al Browse recently published - Information from www.nejm.org

Health Policy · Medicine and Society · Gray Matters protection gained by the booster shot was not expected to reach its maximal capacity  - Information from www.nejm.org

The New England Journal of Medicine (NEJM) is a weekly general medical journal that publishes new medical research and review articles and editorial  - Information from www.nejm.org

Not Dying Alone When the wife of a severely ill patient with Covid19 is told she cant visit him her anger quickly gives way to pleading  - Information from www.nejm.org

There are currently 7042 active senior and nonresident fellows of the Massachusetts Medical Society who receive the Journal with all the regularity that  - Information from www.nejm.org

Augmentation of citalopram with either sustainedrelease bupropion or buspirone appears to be useful in actual clinical settings Augmentation  - Information from www.nejm.org

BackgroundAn accurate noninvasive test could improve the effectiveness of colorectalcancer screening MethodsWe compared a noninvasive  - Information from www.nejm.org

Stercoral Ulcer List of authors J G MUMFORD MD February 11 1897 Boston Med Surg J 1897 136:129131 DOI: 101056/NEJM189702111360604 - Information from www.nejm.org

angina [class ≥II on the Canadian Cardiovascular Society scale At 3 months the mean (±SD) heart rate of the patients was 607±90  - Information from www.nejm.org

The unilateral presentation suggested a local as opposed to systemic cause The stenosis of the right popliteal artery was the presumed source  - Information from www.nejm.org

Intravenous Immune Globulin and Pseudohyponatremia To the Editor: A 49yearold woman admitted with typical Guillain–Barré syndrome was  - Information from www.nejm.org

Summary Genome sequencing is often pivotal in the diagnosis of rare diseases but many of these conditions lack specific treatments - Information from www.nejm.org

A low intake of fiber from fruits appeared to contribute to the risk of colon cancer but this relation was not statistically independent of  - Information from www.nejm.org

Vitamin B 12 Deficiency Vitamin B12 deficiency causes reversible megaloblastic anemia demyelinating neurologic disease or both Autoimmune  - Information from www.nejm.org

31 issue]) on ecigarette or vaping product use–associated lung injury (EVALI) particularly the role of bronchoscopy in the diagnostic workup  - Information from www.nejm.org

et al for the TULIP2 Trial Investigators - Information from www.nejm.org

Prespecified Analysis versus Post hoc Analysis A prespecified subgroup analysis is one that is planned and documented before any  - Information from www.nejm.org

Fatigue Arthralgias a Mouth Ulcer and a Rash draw the wound edges together as the opening of a purse is closed by a purse string - Information from www.nejm.org

sons Disease Rating Scale (UPDRS) between baseline and 42 weeks The Hoehn–Yahr scale which ranges from 1 to 5 represents stages of  - Information from www.nejm.org

CAR T Cells for Refractory Systemic Lupus Erythematosus A 20yearold woman with refractory SLE with active lupus nephritis (WHO class IIIA)  - Information from www.nejm.org

Israel (PDF) the Department of Neurol analysis based on the Unified Parkinsons Disease Rating Scale (UPDRS a 176point - Information from www.nejm.org

The New England Journal of Medicine (NEJM) is a weekly general medical journal that publishes new medical research and review articles and editorial  - Information from www.nejm.org

Thirtysix percent of the 98 asymptomatic subjects had normal disks disk abnormalities were Schmorls nodes (herniation of the disk into  - Information from www.nejm.org

American Heart Association (AHA) American Heart Association Scientific Sessions 2020 November 13–17 Read new research studies and commentary published in  - Information from www.nejm.org

They cannot heat bottlesthey clutch at cigarette logjamsand drown in a sea of beerthe truck discharges at their doorAnd if they water down  - Information from www.nejm.org

Pyridoxine (B6) Suppresses the Rise in Prolactin and Increases the Rise in Growth Hormone Induced by Exercise Your archive account will be  - Information from www.nejm.org

Inflammation is widely believed to play a central role in the pathogenesis of atherosclerosis and acute coronary events12 Although  - Information from www.nejm.org

Vaccinology and Covid19 In this audio interview conducted on October 14 2020 the editors discuss the fundamental concepts behind  - Information from www.nejm.org

or vasa vasorum penetrating the wall structure of pulmonary vessels a dynamic interdependent influence of multiple risk factors  - Information from www.nejm.org

Background Extrapolation from studies in the 1980s suggests that smoking causes 25% of deaths among women and men 35 to 69 years of age in  - Information from www.nejm.org

can remove large amounts of body fat is a poten tial treatment for the metabolic (waist circumference blood pressure plasma lipid - Information from www.nejm.org

Early temporary pelvic stabilization can reduce hemorrhage from pelvicring fractures This video demonstrates the use of pelvic sheeting to  - Information from www.nejm.org

Physical examination revealed two ulcerated lesions with irregular margins on the hard palate (Panel A) and gingival mucosa (Panel B) - Information from www.nejm.org

When the Journal took up the topic in 2003 with a debate about the role of race in medicine one side argued that racial and ethnic categories  - Information from www.nejm.org

N Engl J Med 2019 380:10221032 DOI: 101056/NEJMoa1803917 Chinese Translation 中文翻译 Article Figures/Media - Information from www.nejm.org

ibrutinib (at a dose of 420 mg per day until disease progression or an unacceptable level of side effects occurred) and rituximab (50 mg  - Information from www.nejm.org

TNTIL ten or fifteen years ago1 knowledge of red cell production was based primarily on morphologic observation During the past decade however  - Information from www.nejm.org

To the Editor: A 35yearold woman with diabetes presented with pruritic erythematous urticated plaques at insulininjection sites  - Information from www.nejm.org

S3) but no grade 3 or 4 events and no cases of acute rejection This may reflect ongoing mRNA vaccine–induced Bcell stimulation  - Information from www.nejm.org

Dr Howard Brody argues that to help control costs each specialty society create a “Top Five” list of common tests or treatments that  - Information from www.nejm.org

Other causes of cystic splenic masses such as parasitic cysts various vascular tumors fluid collections related to pancreatitis benign tumors of the spleen  - Information from www.nejm.org

Published continuously for over 200 years NEJM delivers highquality than 16000 research and other submissions for consideration for publication - Information from www.nejm.org

Abstract Background Adultonset inflammatory syndromes often manifest UBA1 isoform homologue in zebrafish caused systemic inflammation - Information from www.nejm.org

The New England Journal of Medicine (NEJM) is a weekly general medical journal that publishes new medical research and review articles and editorial  - Information from www.nejm.org

antibodies against PF4 which clinically mimics autoimmune heparininduced thrombocytopenia (Funded by the German Research Foundation)  - Information from www.nejm.org

Severe Symptoms of Hyperhistaminemia after the Treatment of Acute Promyelocytic Leukemia with Tretinoin (alltransRetinoic Acid) - Information from www.nejm.org

it causes to do harm—while the inflammation is yet recent and active But though pain may have ceased and no fever remains and the pa tient is not conscious  - Information from www.nejm.org

et al for the Hemodialysis (HEMO) Study Group - Information from www.nejm.org

The New England Journal of Medicine (NEJM) is a weekly general medical journal that publishes new medical research and review articles and editorial  - Information from www.nejm.org

most of that countrys Covid19 cases — faced a hospital bed shortage Ethical Values for Rationing Health Resources in a Pandemic - Information from www.nejm.org

Death by Stereotype? Unmarried patients are less likely to survive cancer Is that at least partly because of physicians biases in  - Information from www.nejm.org

due to Shiga toxinproducing Escherichia coli (STEC) serotype O104 Germany May 2011 Hauri A Gotsch U Strotmann I et al - Information from www.nejm.org

Figure 1 Structure of Meningococcal Outer Membrane Showing Variability of OuterMembrane Proteins and Capsule Used in Vaccines and Interaction  - Information from www.nejm.org

From 2010 through 2014 we enrolled communitydwelling persons in Australia and the United States who were 70 years of age or older (or ≥65 - Information from www.nejm.org

Lanadelumab (DX2930) is a new kallikrein inhibitor with the potential for prophylactic treatment of hereditary angioedema with C1 inhibitor  - Information from www.nejm.org

Tanya Eble MS Baylor College of Medicine Houston TX Yasemen Eroglu MD Oregon Health and Science University Portland OR Deanna  - Information from www.nejm.org

Cyclic GMP is formed from GTP by guanylyl cyclase and can be hydrolyzed and inactivated by phosphodiesterase Among other functions it can also  - Information from www.nejm.org

Nonintervertebral disk abnormalities such as facet arthropathy On MRI examination of the lumbar spine many people without back pain - Information from www.nejm.org

Abstract Background The perinatal and maternal consequences of induction of labor at 39 weeks among lowrisk nulliparous women are uncertain  - Information from www.nejm.org

The contraindications to the use of verapamil include a history suggestive of ventricular dysfunction concomitant treatment with beta  - Information from www.nejm.org

RNA (mRNA) vaccines against coronavirus disease 2019 (Covid19) myocarditis in male teenagers emerged as a possible rare side effect  - Information from www.nejm.org

Examples of Race Correction in Clinical Medicine To illustrate the potential dangers of such practices we have compiled a partial list of race  - Information from www.nejm.org

A novel human coronavirus that is now named severe acute Viability of SARSCoV1 and SARSCoV2 in Aerosols and on Various Surfaces - Information from www.nejm.org

Even the most skeptical observer should be impressed by the rapidity of scientific advances in our management of colorectal cancer  - Information from www.nejm.org

In 2019 as the “public charge” rule made its way through the US court system many lowincome immigrant parents of American children in  - Information from www.nejm.org

The Seldinger method of chesttube insertion is performed with the use of 14French or smaller chest drains usually under ultrasound guid - Information from www.nejm.org

Introduction · Health Impacts of ModeratetoSevere Pandemics · Health System Capacity · Ethical Values for Rationing Health Resources in a  - Information from www.nejm.org

Abstract Background Although the national obesity epidemic has been well documented less is known about obesity at the US state level - Information from www.nejm.org

difficult and now quite common diagnostic dilemma Failure to recognize the exact nature of this dilemma may lead to serious errors of  - Information from www.nejm.org

In many countries the availability of vaccines has marked a turning point in the Covid19 pandemic Although the vaccines are imperfect  - Information from www.nejm.org

We examined the prevalence of abnormal findings on magnetic resonance imaging We performed MRI examinations on 98 asymptomatic people - Information from www.nejm.org

and Michael Blaivas MD for the Society of Radiologists in Ultrasound Multispecialty Panel on Early First Trimester Diagnosis of Miscarriage - Information from www.nejm.org

The New England Journal of Medicine (NEJM) is a weekly general medical journal that publishes new medical research and review articles and editorial  - Information from www.nejm.org

Because of genetic and structural receptor conservation among mammalian species many of these animal betacoronaviruses are “preadapted” for  - Information from www.nejm.org

Please note the following: •Your letter must be typewritten and triplespaced disease process from 1987 to 1994 as reported by Ros - Information from www.nejm.org

VITT is a severe complication after ChAdOx1 nCoV19 vaccination Upfront treatment remains anticoagulation and IVIG Although further  - Information from www.nejm.org

systemic lupus erythematosus who have glomerulone excretion and serum creatinine IgG antidsDNA antibody cryo - Information from www.nejm.org

JOURNALS The New England Journal of Medicine opens in new tab · NEJM Catalyst Innovations in Care Delivery  - Information from www.nejm.org

for the EMPAREG OUTCOME Investigators (Funded by Boehringer Ingelheim and Eli Lilly EMPAREG OUTCOME ClinicalTrialsgov number  - Information from www.nejm.org

This content requires an NEJMorg account Create a free account now Already have an account? Sign in Images in Clinical MedicineFree Preview  - Information from www.nejm.org

Major Health Risks Associated with Climate Change the economic benefits arising from reduced air pollution range from $50 to $380 per  - Information from www.nejm.org

Parens Patriae — The Sovereign Power of Guardianship MARK Twain vacationing in the mountains near Vienna one evening fell over a 75foot cliff He lay at  - Information from www.nejm.org

Background The order and magnitude of pathologic processes in Alzheimers disease are not well understood partly because the disease  - Information from www.nejm.org

The contraindications to the use of verapamil include a history suggestive of ventricular dysfunction concomitant treatment with beta  - Information from www.nejm.org

In conclusion sirtuins are a unique class of proteins that link protein acetylation to metabolism and exert profound effects on mammalian  - Information from www.nejm.org

Editorial from The New England Journal of Medicine — The Annual Meeting of the Harvard Medical School Alumni Association - Information from www.nejm.org

The New England Journal of Medicine (NEJM) is a weekly general medical journal that publishes new medical research and review articles and editorial  - Information from www.nejm.org

The New England Journal of Medicine (NEJM) is a weekly general medical journal that publishes new medical research and review articles and editorial  - Information from www.nejm.org

Acute kidney injury is a potential complication of severe rhabdomyolysis regardless of whether the rhabdomyolysis is the result of trauma or  - Information from www.nejm.org

Acute kidney injury is a potential complication of severe rhabdomyolysis regardless of whether the rhabdomyolysis is the result of trauma  - Information from www.nejm.org

Rhabdomyolysis and Acute Kidney Injury · Article · Article Categories · Resources · About Us · Subscriptions · Stay Connected · Follow Us - Information from www.nejm.org

In two patients with rhabdomyolysis and acute kidney injury the mean serum myoglobin clearance with a single dialysis treatment was 59% A 4  - Information from www.nejm.org

BackgroundStudies have suggested that sickle cell trait elevates the risks of exertional rhabdomyolysis and death We conducted a study of  - Information from www.nejm.org

JOURNALS The New England Journal of Medicine opens in new tab · NEJM Catalyst Innovations in Care Delivery  - Information from www.nejm.org

Abstract Rhabdomyolysis with myoglobinuria from nontraumatic causes was the sole identifiable explanation for acute renal failure in 15  - Information from www.nejm.org

Abstract Background The perinatal and maternal consequences of induction of labor at 39 weeks among lowrisk nulliparous women are uncertain  - Information from www.nejm.org

Since March 2020 Asian Americans have experienced an alarming increase in racial discrimination and racially motivated violence - Information from www.nejm.org

The New England Journal of Medicine (NEJM) is a weekly general medical journal that publishes new medical research and review articles and editorial  - Information from www.nejm.org

difficult and now quite common diagnostic dilemma Failure to recognize the exact nature of this dilemma may lead to serious errors of  - Information from www.nejm.org

Operationalizing the value of maximizing benefits means that Conversely treatments for coronavirus address urgent need meaning that a  - Information from www.nejm.org

This article was published on December 15 2021 at NEJMorg DOI: 101056/NEJMoa2116185 sored protocol safety review team and safety ef - Information from www.nejm.org

et al for the TULIP2 Trial Investigators - Information from www.nejm.org

DENTAL caries (tooth decay) is a chronic infectious disease in which the active agent or agents are members of the indigenous oral flora - Information from www.nejm.org

milk 1 AM Dec 23d—Pulse 170 and up wards and difficult to count to drink his milk and medicine Probably no disease to which the human - Information from www.nejm.org

However after acceptance for publication authors may designate more than A Disclosure Form for Work Submitted to Medical Journals — A Proposal from  - Information from www.nejm.org

The New England Journal of Medicine (NEJM) is a weekly general medical journal that publishes new medical research and review articles and editorial  - Information from www.nejm.org

Abstract We evaluated the use of the urinary anion gap (sodium plus potassium minus chloride) in assessing hyperchloremic metabolic acidosis - Information from www.nejm.org

IN the late afternoon of June 9 1953 a tornado unexpectedly struck a section of Worcester County Massachusetts and in about twenty minutes created a  - Information from www.nejm.org

Postinfectious Epigenetic Immune Modifications — A DoubleEdged Sword List of authors Andrew R DiNardo MD Mihai G Netea MD  - Information from www.nejm.org

and it contained visible ribs (black arrow) an eye (black arrowhead) a foot (white arrow) and a helical trivascular umbilical cord - Information from www.nejm.org

Secondary outcomes did not differ significantly between the two groups Adverse events with the active drug were mainly gastrointestinal - Information from www.nejm.org

The rate of functional recovery on the Disability Rating Scale (DRS range 0 to 29 with higher scores indicating greater disability) was  - Information from www.nejm.org

To the Editor: Geisler et al (June 27 issue)1 attribute efficacy to GM1 (Sygen) the Fidia Pharmaceutical Corporations bovinebrain  - Information from www.nejm.org

MEDIATED CYTOLYSIS Unlike humoral immune responses which are me diated through antibodies and complement and can - Information from www.nejm.org

In the open trial in which patients who initially underwent sham exchange were treated with plasma exchange the neuropathy disability score (P  - Information from www.nejm.org

The ClinicalTrialsgov Results Database — Update and Key Issues List of authors Deborah A Zarin MD Tony Tse PhD  - Information from www.nejm.org

This article was published on November 16 2019 at NEJMorg Dangas GD Weitz JI Giustino G Makkar R Mehran R Prosthetic heart  - Information from www.nejm.org

When thromboangiitis obliterans occurs in unusual locations the diagnosis should be made only when histopathological examination identifies the  - Information from www.nejm.org

Many US patients do not adhere to prescribed medication regimens Interview with Dr Lisa Rosenbaum on nonadherence and ways to improve  - Information from www.nejm.org

Nineteen days before admission a sonogram revealed a thickened The remainder of the fetal cord and placental anatomy appeared normal - Information from www.nejm.org

classically become diminished in amplitude and delayed in time (parvus et tardus) Pathophysiologic Stages of Mitral Regurgitation - Information from www.nejm.org

Results A total of 1327 semen samples from 184 men and 1038 urine samples from 183 men were obtained 14 to 304 days after illness onset ZIKV  - Information from www.nejm.org

Virginia showing that tobacco was by law made a means " for the defraying of all public charges and impositions" We see therefore lhat - Information from www.nejm.org

Background and Methods Lateral internal sphincterotomy the most common treatment for chronic anal fissure may cause permanent injury to  - Information from www.nejm.org

Early temporary pelvic stabilization can reduce hemorrhage from pelvicring fractures This video demonstrates the use of pelvic sheeting to  - Information from www.nejm.org

Abstract Background Safe effective vaccines against coronavirus disease 2019 (Funded by BioNTech and Pfizer ClinicalTrialsgov number  - Information from www.nejm.org

Abstract Background Safe effective vaccines against coronavirus disease 2019 (Covid19) are urgently needed in children younger than 12  - Information from www.nejm.org

4 weeks after treatment and during the entire 3 months of the study Among patients who had IBS without constipation treatment with  - Information from www.nejm.org

LSD — A Dangerous Drug SINCE the accidental discovery of LSD (dlysergic acid diethylamide) in 1943 this drug with its extraordinary effects has been the  - Information from www.nejm.org

Zika virus is rapidly spreading throughout the Americas and the Caribbean The association with microcephaly has led the WHO to declare a  - Information from www.nejm.org

Anemia of inflammation (also referred to as anemia of chronic disease) has been recognized for more than 60 years as a mild to moderately  - Information from www.nejm.org

The Nature of Aggression during Epileptic Seizures · Antonio V DelgadoEscueta MD · Richard H Mattson MD · Lambert King MD · Eli S - Information from www.nejm.org

Radiologists in Ultrasound Multispecialty Panel on Early First Trimester Diagnosis of Miscarriage and Exclusion of a Viable Intrauterine  - Information from www.nejm.org

Underweight was most strongly associated with an increased risk of death among former and current smokers (Table 2 and Table 3 and Figure 1C and  - Information from www.nejm.org

Ipecac — Syrup vs Fluidextract October 26 1961 N Engl J Med 1961 265:861 DOI: 101056/NEJM196110262651718 No extract is available for articles  - Information from www.nejm.org

The New England Journal of Medicine (NEJM) is a weekly general medical journal that publishes new medical research and review articles and editorial  - Information from www.nejm.org

Clinical evidence is the material with which the physician works and a meticulous history and physical examination are paramount The  - Information from www.nejm.org

Submit Your Permission Request Using RightsLink Simply visit NEJMorg and locate the article or video from which you seek to reuse content - Information from www.nejm.org

However the safety and efficacy of cryoballoon ablation as initial or drug dose adjustment evaluated in a Kaplan–Meier analysis) - Information from www.nejm.org

fetal growth restriction may be one of the major de terminants Fetuses that are small for gestational and ICD10 respectively) and were noted at the - Information from www.nejm.org

Enteral DHA supplementation at a dose of 60 mg per kilogram per day did (Funded by the Australian National Health and Medical Research  - Information from www.nejm.org

Thinking this resembled sarcoma he called the condition “multiple benign sarcoid of the skin” Since sarcoidosis was last reviewed in the  - Information from www.nejm.org

5 to6day training session conducted by the In items) and the Harvard Trauma Questionnaire (HTQ)19 to assess PTSD symptoms (16 items)  - Information from www.nejm.org

After oral administration of molnupiravir NHC circulates systemically and is either guanosine or adenosine during viral replication - Information from www.nejm.org

The response to the Covid19 pandemic is a prime example of how rapidly new vaccines can now be designed By the time the WHO declared Covid19 - Information from www.nejm.org

The US Food and Drug Administration has the overriding purpose of protecting the Pure Food and Drug Act The act sought to prevent the  - Information from www.nejm.org

Shatzman (Medicine): A 24yearold man was admitted to this hospital in the spring of 2020 because of headache and coronavirus disease 2019 (  - Information from www.nejm.org

Rheumatoid arthritis is a common autoimmune disease that is associated with progressive disability systemic complications early death and  - Information from www.nejm.org

Background Controlled clinical trials have shown that betablockers can produce hemodynamic and symptomatic improvement in chronic heart  - Information from www.nejm.org

Moriah Bergwerk MB BS Tal Gonen BA Yaniv Lustig PhD Sharon Amit MD breakthrough infection was defined as the de - Information from www.nejm.org

See text for details Adrenergic receptors are members of a large superfamily of receptors linked to guaninenucleotide–binding proteins (G  - Information from www.nejm.org

The hallmarks of necrotizing fasciitis are friable superficial but the clinical approaches to diagnosis and treatment are similar - Information from www.nejm.org

Enrollment of patients without a docu mented history of previous pancreatitis was patients with fasting baseline triglyceride levels - Information from www.nejm.org

Summary of World Health Organization (WHO) Process of Virus Selection for Annual Influenza Vaccines Readministration of influenza vaccine has  - Information from www.nejm.org

We also present the data using the ulcerative colitis diseaseactivity index for which we defined both: oral prednisolone and foam enemas in 2 pred - Information from www.nejm.org

Buergers Test The test of leg elevation known as Buergers test is used to detect poor blood flow in a critically ischemic limb - Information from www.nejm.org

Abstract Background The perinatal and maternal consequences of induction of labor at 39 weeks among lowrisk nulliparous women are uncertain  - Information from www.nejm.org

A high rate of treatment discontinuation occurred in this study because of the severity of the underlying disease only 46% of the patients in  - Information from www.nejm.org

Atogepant is an orally available smallmolecule CGRP receptor antagonist with an elimination halflife of approximately 11 hours maximum  - Information from www.nejm.org

xml · Effects of Pentylenetrazol on Senile Patients — A Clinical Study JB Andosca AT the Long Island Hospital in Boston the patients are mainly  - Information from www.nejm.org

amide anuria or who recovered when obstruction dependent of tubular obstruction by crystals seems was relieved by ureteral catheterization - Information from www.nejm.org

Reduction of Postoperative Pain by Encouragement and Instruction of Patients — A Study of DoctorPatient Rapport · Lawrence D Egbert MD · George E Battit  - Information from www.nejm.org

A correction has been published 1 · Original Article A Comparison of Osteopathic Spinal Manipulation with Standard Care for Patients with  - Information from www.nejm.org

including loss over an observation period of at least 48 hours of measurable cranialnerve function and spontaneous movements  - Information from www.nejm.org

Regulating Drug Prices while Increasing Innovation Editors Note: This article was published on April 14 2020 at NEJMorg - Information from www.nejm.org

The Acute Respiratory Distress Syndrome Network Members of the Acute Respiratory Distress Syndrome (ARDS) Network are listed in the  - Information from www.nejm.org

to estimate the effectiveness of the booster dose in the population years) and death (≥60 years) owing to smaller numbers of cases - Information from www.nejm.org

Since March 2020 Asian Americans have experienced an alarming increase in racial discrimination and racially motivated violence - Information from www.nejm.org

International medical graduates constitute between 23 and 28 percent of physicians in the United States the United Kingdom Canada  - Information from www.nejm.org

The New England Journal of Medicine (NEJM) is a weekly general medical journal that publishes new medical research and review articles and editorial  - Information from www.nejm.org

for the Coalition Covid19 Brazil I Investigators of liverenzyme levels were more frequent in patients receiving hydroxychloroquine  - Information from www.nejm.org

The diabetic neuropathies include a variety of syndromes that differ in their clinical manifestations prognoses and in some instances  - Information from www.nejm.org

This paradoxical aciduria in the midst of alkalemia is evidence that blood pH depends on strong ion balance The alkalemia will be corrected  - Information from www.nejm.org

New England Journal of Medicine — Gingival Hypertrophy and Leukemia Acute myeloid leukemia (AML) was suspected and AML subtype M4  - Information from www.nejm.org

97% [68 of 699] difference −30 percentage points 95% confidence interval −59 to −01) Results of subgroup analyses were largely  - Information from www.nejm.org

A separate disclosure policy applies to review articles and editorials which comment on published articles but do not present new research The Journal - Information from www.nejm.org

The leading causes of death varied between younger and older children Among children 1 to 4 years of age drowning was the most common cause of  - Information from www.nejm.org

This article reviews scientific advances in the prevention and treatment of substanceuse disorder and related developments in public policy  - Information from www.nejm.org

Newly available data permit for the first time reliable crossnational comparisons of mortality among persons 80 years of age or older - Information from www.nejm.org

of a central venous catheter in the internal jugular vein with the use of one of several variations of the Seldinger technique - Information from www.nejm.org

Maxillary sinus 2 Ethmoidal bulla 3 Ethmoidal cells 4 Frontal sinus 5 Uncinate process 6 Middle turbinate 7 Inferior turbinate - Information from www.nejm.org

The pathophysiologic features of diabetic neuropathy a common and disabling longterm complication of diabetes mellitus  - Information from www.nejm.org

Abstract Background When patients with a tracheostomy tube reach a stage in their care at which decannulation appears to be possible  - Information from www.nejm.org

A Novel Coronavirus from Patients with Pneumonia in China 2019 List of authors Na Zhu PhD Dingyu Zhang MD Wenling Wang PhD  - Information from www.nejm.org

in the gene encoding C1 inhibitor (also called C1 esterase inhibitor) that lead to overactivation of the kallikrein–bradykinin cascade - Information from www.nejm.org

The patient received Crotalidae polyvalent immune Fab antivenin before being admitted to a hospital Laboratory studies revealed coagulopathy  - Information from www.nejm.org