Gap vs gef

GEFs and GAPs: Critical Elements in the Control of Small G

www.sciencedirect.com

In general GEFs turn on signaling by catalyzing the exchange from Gproteinbound GDP to GTP whereas GAPs terminate signaling by inducing GTP - Information from www.sciencedirect.com

Information accuracy 100%
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C7 GAPs and GEFs TBA Biology LibreTexts

bio.libretexts.org

GAP GTPase Activating Proteins: These proteins facilitate hydrolysis of bound GTP hence down regulating the activity of the G protein · GEF - Information from bio.libretexts.org

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Guanine nucleotide exchange factor Wikipedia

en.wikipedia.org

Guanine nucleotide exchange factors (GEFs) are proteins or protein domains that activate monomeric GTPases by stimulating the release of guanosine - Information from en.wikipedia.org

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Synaptic GAP and GEF Complexes Cluster Proteins Essential

www.nature.com

GTPaseactivating proteins (GAPs) and guanine exchange factors (GEFs) play essential roles in regulating the activity of small GTPases - Information from www.nature.com

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Ras activation revisited: role of GEF and GAP systems De

www.degruyter.com

Three decades of intense Ras research have disclosed various families of guanine nucleotide exchange factors (GEFs) and GTPase activating - Information from www.degruyter.com

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Regulation of Small GTPases by GEFs GAPs and GDIs

journals.physiology.org

Several GEF catalytic domains have been crystallized both V We review the other situations below (FIGURE 4) - Information from journals.physiology.org

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2 assays to assess GEF and GAP activity tebubios blog

www.tebu-bio.com

It has been shown that the GAP family of proteins is large (70 members) and potentially important for changing a cell from a normal to disease - Information from www.tebu-bio.com

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GProtein and GTPase Switching Mechanism YouTube

www.youtube.com

- Information from www.youtube.com

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GAPs and GEFs of the Small Gproteins Rho Rac and Cdc42

www.cytoskeleton.com

Cytoskeleton is the preeminent supplier of GAP and GEF proteins These products contain the active domains and have been fully QCd for high activity - Information from www.cytoskeleton.com

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CHAPTER 2 RASGEFS AND RAS GAPS Springer Link

link.springer.com

lies of cellular proteins possessing GAP or GEF activity on any of the classical Arozarena I Aaronson DS Matallanas D Sanz V Ajenjo N - Information from link.springer.com

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Probing the GTPase cycle with realtime NMR CiteSeerX

citeseerx.ist.psu.edu

been extensively used for fluorescencebased GAP and GEF assays but they do not dissect the contributions of GAP versus GEF activ - Information from citeseerx.ist.psu.edu

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ARF GTPases and their GEFs and GAPs Molecular Biology

www.molbiolcell.org

Thus the triad of GEF–GTPase–GAP can be viewed as a minimal component Examples include the duplication that gave rise to class I versus - Information from www.molbiolcell.org

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Detection of Rho GEF and GAP activity Portland Press

portlandpress.com

In cellbased assays a GEF or GAP may be exogenously expressed or suppressed in glycerol was added to 10% (v/v) final concentration the proteins were - Information from portlandpress.com

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A Rab GAP cascade defines the boundary between PNAS

www.pnas.org

Rabs are activated by specific guanine nucleotide exchange factors (GEFs) and inactivated by GTPaseactivating proteins (GAPs) GEF cascades - Information from www.pnas.org

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Regulation of membrane traffic by Rab GEF and GAP cascades

www.tandfonline.com

In principle by locating its GEF on one compartment and its GAP on another Myosin V transports secretory vesicles via a Rab GTPase cascade and - Information from www.tandfonline.com

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(PDF) In vitro GEF and GAP assays ResearchGate

www.researchgate.net

GEF catalyzed nucleotide exchange and the GAPstimulated GTPhydrolysis in a ﬂuorescence cuvette in GEF buffer with the GEF protein at a ﬁnal volume - Information from www.researchgate.net

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Targeting the Small GTPase Superfamily through Their

onlinelibrary.wiley.com

This review explores the molecules targeting the GEF GAP and GDI GTPase Ras (14 GAPs) versus the larger Rho family (>66 GAPs) - Information from onlinelibrary.wiley.com

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Gap vs gef information was found here: https://onlinelibrary.wiley.com/doi/full/10.1002/anie.201900585

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Guanine nucleotide exchange factors for Rho GTPases

genesdev.cshlp.org

GTPase activating proteins (GAPs) accelerate the intrinsic GTPase activity of Rho family RasGEF RhoGAP RanGEF PDZ or additional PH domains (Fig - Information from genesdev.cshlp.org

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The roles of GTPaseactivating proteins in regulated cell death

jhoonline.biomedcentral.com

GTPaseactivating protein (GAP) is a negative regulator of GTPase protein In that process hyperactive HRas activates the Rac1 GEF - Information from jhoonline.biomedcentral.com

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Screening GAPs and GEFs with the Transcreener GDP Assay

www.bellbrooklabs.com

detection of GTPaseaccelerating proteins (GAPs) and guanine nucleotide exchange unbiased biochemical assay platform for measuring Rho GEF catalytic - Information from www.bellbrooklabs.com

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Small GTPases and their guaninenucleotide exchange factors

journals.lww.com

Their GEFs and GAPs are regulated by a range of mechanisms including phosphorylation Endothelial GPCRs signal through cAMP the RapGEF Epac and Rap1 - Information from journals.lww.com

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Coordination of membrane traffic through rab GEF and GAP

grantome.com

Rabs constitute the largest branch of the Ras GTPase superfamily with ten members in yeast and more than 60 in mammalian cells - Information from grantome.com

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RacGEF/Rac Signaling and Metastatic Dissemination in Lung

www.frontiersin.org

The inactivation of Rac1 is mediated by GTPaseActivating Proteins (GAPs) which are responsible for accelerating the intrinsic GTP - Information from www.frontiersin.org

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The Role of Mg2+ Cofactor in the Guanine Nucleotide

www.jbc.org

to be negatively regulated by free Mg2+ and GEF bind ing to Rho GTPase resulted in a the GEF and GAPcatalyzed reactions of Rho family GTPases - Information from www.jbc.org

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Detection of Rho GEF and GAP activity through a sensitive

www.semanticscholar.org

Assay of Cdc42 Rac and Rho GTPase activation by affinity methods V Benard G Bokoch - Information from www.semanticscholar.org

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Superoxide Inhibits Guanine Nucleotide Exchange Factor

pubs.acs.org

(10) GAPs downregulate the level of activity of small GTPases by A number of Rasspecific GEF (RasGEF) proteins have been identified - Information from pubs.acs.org

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Structural Insights into the Regulation Mechanism of Small

www.mdpi.com

Guanosine triphosphate (GTP)bound and guanosine diphosphate (GDP)bound GTPases (lipidated forms) are shown as red and blue circles respectively GAP and GEF - Information from www.mdpi.com

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Stressdependent inhibition of cell polarity through bioRxiv

www.biorxiv.org

unbalancing the GEF/GAP regulation of Cdc42 as a Cdc42 GAP localized to cell tips but its activity of Cdc42 (GTP vs - Information from www.biorxiv.org

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Gap vs gef information was found here: https://www.biorxiv.org/content/10.1101/2021.08.10.455852v1.full.pdf

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In vivo identification of GTPase interactors by mitochondrial

elifesciences.org

MitoID can also efficiently identify effectors and GAPs of Rho and Ras of the Rheb GAP (Manning and Cantley 2003) and the VATPase - Information from elifesciences.org

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Gap vs gef information was found here: https://elifesciences.org/articles/45916

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Stressdependent inhibition of polarized cell growth through

doi.org

The GAPs Rga3/6 and the GEF Gef1 are direct targets of Sty1 kinase • Increased GAP activity at the cell poles mediates Cdc42 - Information from doi.org

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RhoA G17A Agarose Beads (Active RhoGEF) (ab211183)

www.abcam.com

Similar to Ras mutants constitutively active or dominant negative Rho GTPase mutants have been used to bind to RhoGAP and effectors or to RhoGEFs - Information from www.abcam.com

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G Protein Activation without a GEF in the Plant Kingdom PLOS

journals.plos.org

Moreover the ratio of change in synonomous vs nonsynonous residues (dn/ds) in comparing GAP activity of RGS toward plant Gα subunits - Information from journals.plos.org

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Governance Challenges Gaps and Management GEF

www.thegef.org

Governance Challenges Gaps and Management Opportunities in II IV and V establish a comprehensive system of environmental im - Information from www.thegef.org

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GTPase Biology: New Tools to the Rescue Promega

www.promega.com.cn

GTPaseGlo™ assay principle • Applications for the GTPaseGlo™ assay • Intrinsic GTPase activity • GAPstimulated GTPase activity • GEF activity - Information from www.promega.com.cn

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Local and global Cdc42 guanine nucleotide exchange factors

journals.biologists.com

Control of Cdc42 activity by GTPaseactivating proteins (GAPs) and guanine of a local versus a global GEF might influence the NETO transition - Information from journals.biologists.com

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Gap vs gef information was found here: https://journals.biologists.com/jcs/article/131/14/jcs216580/56842/Local-and-global-Cdc42-guanine-nucleotide-exchange

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The GAPs GEFs and GDIs of heterotrimeric Gprotein alpha

www.ijbs.com

Addition of both RIC8 GEF and RGS7 GAP activities should dramatically accelerate steadystate GTP hydrolysis vs the basal condition in (A) up to whichever - Information from www.ijbs.com

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Multiple Types of Guanine Nucleotide Exchange JStage

www.jstage.jst.go.jp

GAP GTPaseactivating protein GEF guanine nucleotide exchange factor RA membrane trafficking proteins including vSNARE and the retromer complex - Information from www.jstage.jst.go.jp

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A Homogenous Bioluminescent System for Measuring

www.liebertpub.com

The GTPase/GAP/GEFGlo assay system enables monitoring of GTPase extreme differentiation between binding of the antibody to GDP vs - Information from www.liebertpub.com

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Putative Vitis vinifera Rop and RabGAP GEF and GDI

academic.oup.com

proteins in the V vinifera genome is studied here The primary characterization of members of the grapevine GAP GEF and GDI families - Information from academic.oup.com

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The dynamics of spatiotemporal Rho GTPase signaling

f1000research.com

GEF /GAPmediated Rho GTPase fluxes underlie spatiotemporal signaling patterns Spatiotemporal regulation of GEFs and GAPs - Information from f1000research.com

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Ras GTPase 및 Ras GTPase activating protein과 사람의 질병

www.koreascience.or.kr

이와 같이 Ras GTPase는 GEF와 GAP의 활성으로 세포 안의 스위치를 켜고 끄게 된다 L Upadhyaya M Claes K Beert E Peeters K Mautner V Sloan - Information from www.koreascience.or.kr

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Small Gprotein

www2.nsysu.edu.tw

Proteins promote GTP hydrolysis proteinGTP (active) GDP GEF GAP Vesicular (v)SNAREs on vesicles form complexes with target (t)SNAREs - Information from www2.nsysu.edu.tw

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A Better GTPase Assay for Drug Development Promega

www.promegaconnections.com

And each of these players (GTPase GAP and GEF) are potential targets for drug development Copyright Promega Corporation While Ras and the - Information from www.promegaconnections.com

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G Protein Coupled Receptors (video) Khan Academy

www.khanacademy.org

- Information from www.khanacademy.org

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Figure 1 KRas Mutations in NonSmallCell Lung Cancer

www.hindawi.com

Ras activation/deactivation cycle by GEF (guanine exchange factors) and GAP (GTPase activating proteins) 837306fig001 Follow - Information from www.hindawi.com

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All News Releases Distributed by PR Newswire

www.prnewswire.com

Dec 09 2021 07:08 ETMinter Network v 26 : Up to 100000 limit orders in 5 seconds SOFIA Bulgaria Dec 9 2021 /PRNewswire/ On December 1st - Information from www.prnewswire.com

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Ethiopias Climate Resilient Green Economy UNFCCC

www4.unfccc.int

Ethiopias Climate Resilient Green Economy National Adaptation Plan v GEF Global Environment Fund GeoCLIM Climate Analysis software from the United - Information from www4.unfccc.int

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Applications Open In Africa and Asia For Adaptation SME

mytechdecisions.com

and the private sector plays an important role in filling the gap said Carlos Manuel Rodriguez CEO and Chairperson of the GEF - Information from mytechdecisions.com

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Loh becomes first Singapore player to win Badminton World

www.insidethegames.biz

Loh gradually closed the gap to level at 1313 and successfully maintained the momentum to win the game 2115 - Information from www.insidethegames.biz

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Hcmc earning report 2021 The Promo Group

thepromogroup.co.za

GAAP vs com November 15 at 4:37 PM Healthier Choices Management Corp of our infrastructure bill – and the total investment gap has gone from $2 - Information from thepromogroup.co.za

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Gnuradio file transmission

www.moonlight.co.zw

However there is a big gap We present a simple example of data transmission 3 V) Using a simple GNURadio flowgraph similar to the one that has been - Information from www.moonlight.co.zw

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Warehousing it

es-koyama.jp

Inflections of warehouse (v): (⇒ conjugate) warehouses v 3rd person This gap will widen in coming months as companies struggle to keep up with the An - Information from es-koyama.jp

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Half price books oregon

julieanneines.com

amstar 14 coupons costco us coupon book march 2020 deals gap tennessee weather 2 Muller V slide 4 of 2 - Information from julieanneines.com

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File:GEF and GAP systemjpg Wikimedia Commons

commons.wikimedia.org

English: regulation of GProtein activity by GEF and GAP Deutsch: Regulation der GProtein Aktivität durch GEF und GAP Date Unknown date - Information from commons.wikimedia.org

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6900 xt vs 3070

accompagniadom-rhone.fr

While not necessarily an indicator of overall GeForce RTX 3070 vs Radeon RX 6700 9Slot) $1624 ASUS ROGSTRIXGTX1080TIO11GGAMING GeF RTX 3080 vs RX - Information from accompagniadom-rhone.fr

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Hp omen obelisk gaming desktop

obra.gvsengenhraria.com.br.gvsengenharia.com.br

HP OMEN Obelisk Desktop PC 8751040st vs NZXT BLD Starter PC Plus I have HP OMEN OBELISK 875 Gaming Desktop PC i7 32GB 2TB 4GB GeF 1050Ti HDMI DP DVI - Information from obra.gvsengenhraria.com.br.gvsengenharia.com.br

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Closing the Gap: GEF Experiences in Global Energy Efficiency

books.google.com

The main results of the original incremental cost analysis for the project were derived from the two scenarios (Baseline vs GEF Alternative) for a - Information from books.google.com

Information accuracy 100%
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Vesicle Trafficking in Cancer Page 107 Google Books Result

books.google.com

of GAPs and GEFs such as Rabl 1a there is an overexpression of a constitutively active Rab such as Rab25 or if GAP vs GEF ratios were altered - Information from books.google.com

Information accuracy 100%
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6900 xt vs 3070 Alternative Brand Marketing

worldwideam.alternativebrandmarketing.com

GeForce RTX 3070 vs Radeon RX 6700 XT benchmarks vs 99 9Slot) $1624 ASUS ROGSTRIXGTX1080TIO11GGAMING GeF RTX 3080 vs RX 6900 XT for DCS IL2 - Information from worldwideam.alternativebrandmarketing.com

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Tundra forum 2022

atlantaarearoofing.threeoakstech.com

And there will be two engine options: turbo V6 or hybrid the new Toyota Tundra the sole purpose of that big yawning gap is simply to look dumb 53 - Information from atlantaarearoofing.threeoakstech.com

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Systems Biology Page 99 Google Books Result

books.google.com

GAP Fiatio GEF/GAP Figure 314 The Ras activation cycle VGEFIVGAP dt dt (3 11) v _ k1 I GEE RasGDP and v _ k2 4 CAP RasGTP GEF _ (Kmi + RasGDP) GAP 7 - Information from books.google.com

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Robust Cluster Analysis and Variable Selection

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GEFs and GAPs: Critical Elements in the Control of Small G

C7 GAPs and GEFs TBA Biology LibreTexts

Guanine nucleotide exchange factor Wikipedia

Synaptic GAP and GEF Complexes Cluster Proteins Essential

Ras activation revisited: role of GEF and GAP systems De

Regulation of Small GTPases by GEFs GAPs and GDIs

2 assays to assess GEF and GAP activity tebubios blog

GProtein and GTPase Switching Mechanism YouTube

GAPs and GEFs of the Small Gproteins Rho Rac and Cdc42

CHAPTER 2 RASGEFS AND RAS GAPS Springer Link

Probing the GTPase cycle with realtime NMR CiteSeerX

ARF GTPases and their GEFs and GAPs Molecular Biology

Detection of Rho GEF and GAP activity Portland Press

A Rab GAP cascade defines the boundary between PNAS

Regulation of membrane traffic by Rab GEF and GAP cascades

(PDF) In vitro GEF and GAP assays ResearchGate

Targeting the Small GTPase Superfamily through Their

Guanine nucleotide exchange factors for Rho GTPases

The roles of GTPaseactivating proteins in regulated cell death

Screening GAPs and GEFs with the Transcreener GDP Assay

Small GTPases and their guaninenucleotide exchange factors

Coordination of membrane traffic through rab GEF and GAP

RacGEF/Rac Signaling and Metastatic Dissemination in Lung

The Role of Mg2+ Cofactor in the Guanine Nucleotide

Detection of Rho GEF and GAP activity through a sensitive

Superoxide Inhibits Guanine Nucleotide Exchange Factor

Structural Insights into the Regulation Mechanism of Small

Stressdependent inhibition of cell polarity through bioRxiv

In vivo identification of GTPase interactors by mitochondrial

Stressdependent inhibition of polarized cell growth through

RhoA G17A Agarose Beads (Active RhoGEF) (ab211183)

G Protein Activation without a GEF in the Plant Kingdom PLOS

Governance Challenges Gaps and Management GEF

GTPase Biology: New Tools to the Rescue Promega

Local and global Cdc42 guanine nucleotide exchange factors

The GAPs GEFs and GDIs of heterotrimeric Gprotein alpha

Multiple Types of Guanine Nucleotide Exchange JStage

A Homogenous Bioluminescent System for Measuring

Putative Vitis vinifera Rop and RabGAP GEF and GDI

The dynamics of spatiotemporal Rho GTPase signaling

Ras GTPase 및 Ras GTPase activating protein과 사람의 질병

Small Gprotein

A Better GTPase Assay for Drug Development Promega

G Protein Coupled Receptors (video) Khan Academy

Figure 1 KRas Mutations in NonSmallCell Lung Cancer

All News Releases Distributed by PR Newswire

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